Publications / Citations


If This is True, What Does it Imply? How End-User Antibody Validation Facilitates Insights into Biology and Disease. Sfanos KS, Yegnasubramanian S, Nelson WG, Lotan TL, Kulac I, Hicks JL, Zheng Q, Bieberich CJ, Haffner MC, De Marzo AM. Asian Journal of Urology, Janurary 2019.
Prostate Cancer Biorepository (Flyer). 2018 AACR Annual Meeting. April 14-18, 2018. Chicago, IL.
LuCaP Prostate Cancer Patient-Derived Xenografts Reflect the Molecular Heterogenetiry of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics. Nguyen HM, Vessella RL, Morrissey C, Brown LG, Coleman IM, Higano CS, Mostaghel EA, Zhang X, True LD, Lam HM, Roudier M, Lange PH, Nelson PS, Corey E. The Prostate, May 2017. doi:10.1002/pros.23313.
Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides Baena-Del Valle J , Zheng Q, Hicks J, Fedor H, Trock B, Morrissey C, Core E, Cornish TC, Sfanos KS, De Marzo AM. American Journal of Clinical Pathology. October 2017; doi: 10.1093
Biobanking of Derivatives from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomy Tissues as Part of the Prostate Cancer Biorepository Network Darshan M, Zheng Q, Fedor HL, Wyhs N, Yegnasubramanian S, Lee P, Melamed J, Netto GJ, Trock BJ, De Marzo AM, Sfanos KS. Prostate. 2014 Jan;74(1):61-9. doi: 10.1002/pros.22730. Epub 2013 Sep 21.
Biobanking of Derivatives from Radical Retropubic and Robot−Assisted Laparoscopic Prostatectomy Tissues as part of the Prostate Cancer Biorepository Network (PCBN) Society for Basic Urological Research (SBUR) Meeting. November 15-18, 2012. Miami, FL
Ischemia time monitoring: Experience of the Prostate Cancer Biorepository Network. Pe Benito R, Fedor H, Gorman M, Netto G, Sfanos KS, Kolmer P, Darshan M, Morgan J, Lee P, De Marzo AM, Trock BJ, Melamed JM. ISBER 2012 Annual Meeting & Exhibits. May 15-18 2012. Vancouver, British Columbia, Canada.
The Prostate Cancer Biospecimen Network (PCBN) Pe Benito R, Fedor H, Gorman M, Netto G, Sfanos KS, Kolmer P, Darshan M, Morgan J, Lee P, De Marzo AM, Trock BJ, Melamed JM. ISBER 2012 Annual Meeting & Exhibits. May 15-18 2012. Vancouver, British Columbia, Canada.
Prostate Cancer Biorepository (Flyer). 2012 AACR Annual Meeting. March 31-April 4 2012. Chicago, IL.
Biobanking as Part of the Prostate Cancer Biorepository Network (PCBN): A focus on DNA, RNA and Protein Derivative from Radical Prostatectomy Specimens. Darshan M, Fedor H, Zheng Q, Kolmer P, Pe Benito R, Gorman M, Lee P, Melamed JM, Trock BJ, De Marzo AM, Sfanos KS. OBBR BRN Symposium. February 22-23 2012
Ischemia / Fixation Trial Tissue Microarray. Pe Benito R, Fedor H, Gorman M, Netto G, Sfanos KS, Kolmer P, Darshan M, Morgan J, Lee P, De Marzo AM, Trock BJ, Melamed JM. OBBR BRN Symposium. February 22-23 2012
Prostate Cancer Biorepository Network: Prostate Cancer Specimens for Your Research (Flyer). CDMRP IMPaCT 2011 Conference. March 9-12 2011. Orlando, FL.
The Prostate Cancer Biorepository Network (PCBN). CDMRP IMPaCT 2011 Conference. March 9-12 2011. Orlando, FL.

Studies Utilizing the PCBN Resource

Characterization of RNA-binding motif 3 (RBM3) Protein Levels and Nuclear Architecture Changes in Aggressive and Recurrent Prostate Cancer. Carleton NM, Zhu G, Miller MC, Davis C, Kulkarni P, Veltri RW. Cancer Reports. January 2020; DOI:
High Extra-tumoral Mast Cell Counts are Associated with a Higher Risk of Adverse Prostate Cancer Outcomes. Sullivan HH, Heaphy CM, Kulac I, Cuka N, Lu J, Barber JR, De Marzo AM, Lotan TL, Joshu CE, Sfanos KS. Cancer Epidemiology, Biomarkers & Prevention. January 2020; DOI: 10.1158/1055-9965.EPI-19-0962
Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer. Li Y, Yang R, Henzler CM...Maher CA, Feng FY, de Bono JS, Dehm SM. Clinical Cancer Research, AACR. January 2020; DOI: 110.1158/1078-0432.CCR-19-3023
Souble CD105 is Prognostic of Disease Recurrence in Prostate Cancer Patients. Placencio-Hickok VR, Madhav A, Kim S, Duong F, Angara B, Liu Z, Bhowmick NA. Endocrine-Related Cancer. January 2020; DOI:
IL8 Expression is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer. Maynard JP, Ertunc O, Kulac I, Baena-Del Valle JA, De Marzo AM, Sfanos KS. Molecular Cancer Research. January 2020; DOI: 10.1158/1541-7786.MCR-19-0595
Racial Difference in Prostate Cancer Cell Telomere Lengths in Men with Higher-Grade Prostate Cancer: A Clue to Racial Disparity in Prostate Cancer Outcomes. Heaphy CM, Joshu CE, Barber JR, Davis C, Zarinshenas, De Marzo AM, Lotak TL, Sfanos KS, Meeker AK, Platz EA. Cancer Epidemiology, Biomarkers & Prevention. January 2020; DOI: 10.1158/1055-9965.EPI-19-1462
Enzalutamide-induced PTHIR-mediated TGFBR2 decrease in osteoblasts contributes to resistance in prostate cancer bone metastases. Su S, Coa J...Chen B, Yu H, Li X. bioRxiv. November 2019; DOI:
Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients. Bhagirath D, Dahiya R, Majid S, Tabatabai ZL, Saini S. JOVE. November 2019; DOI: 10.3791/60549
Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer. Glumac PM, Gallant JP, Shapovalova M, Li Y, Murugan P, Gupta S, Coleman I, Nelson PS, Dehm SM, LeBeau AM. Clinical Cancer Research, AACR. November 2019; DOI: 10.1158/1078-0432.CCR-19-1659
Syntaxin 6-Mediated Exosome Secretion Regulates Enzalutamide Resistance in Prostate Cancer. Peak TC, Panigrahi GK, Praharaj PP, Su Y...Vander Griend DJ...Deep G. Molecular Carcinogenesis. November 2019; DOI:
PEG10 Promoter-Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer. Shapovalova M, Lee JK Cancer Research. September 2019; DOI: 10.1158/0008-5472.CAN-19-2181
Centrosome Loss Results in an Unstable Genome and Malignant Prostate Tumors. Wang M, Nagle RB, Knudsen BS, Cress AE, Rogers GC. Oncogene. September 2019; DOI:
Cancer/Testis Antigens Differentially Expressed in Prostate Cancer: Potential New Biomarkers and Targets for Immunotherapies. Kagohara LT, Carleton NM, Takahasi S, Shiraishi T, Mooney SM, Vessella RL, Getzenberg RH, Kulkarni P, Veltri RW. bioRxiv. August 2019; DOI:
COMMD3:BMI1 Fusion and COMMD3 Protein Regulate C-MYC Transcription: Novel Therapeutic Target for Metastatic Prostate Cancer. Umbreen S, Banday MM, Jamroze A, Mansini AP, Ganaie AA, Ferrari MG, Maqbool R, Beigh FH, Murugan P, Morrissey C, Corey E, Konety BR, Saleem M. Molecular Cancer Therapeutics. August 2019; DOI: 10.1158/1535-7163.MCT-19-0150
Multi-Immersion Open-Top Light-Sheet Microscope for High-Throughput Imaging of Cleared Tissues. Glaser AK, Reder NP, Chen Y, Yin C, Wei L, Kang S, Barner LA, Xie W, McCary EF, Mao C, Halpern AR, Stoltzfus CR, Daniels JS, Gerner MY, Nicovich PR, Vaughan JC, True LD, Liu JTC. Nature Communications. July 2019; DOI: 2781.
Comparative Analysis of AR Variant AR-V567es mRNA Detection Systems Reveals Eminent Variability and Questions the Role as a Clinical Biomarker in Prostate Cancer. Bernemann C, Humberg V, Thielen B, Steinestel J, Chen X, Duensing S, Schrader AJ, Boegemann M. Clinical Cancer Research. July 2019; DOI: 10.1158/1078-0432.CCR-18-4276
Molecular Profiling Stratifies Diverse Phenotypes of Treatment-Refractory Metastatic Castration-Resistant Prostate Cancer. Labrecque MP,...Nelson PS, Morrissey C. Journal of Clinical Investigation. July 2019; DOI:
Upregulation of Scavenger Receptor B1 is Required for Steroidogenic and Nonsteroidogenic Cholesterol Metabolism in Prostate Cancer. Gordon JA, Noble JW, Midha A, Derakhshan F, Wang G, Adomat HH, Tomlinson Guns ES, Lin YY, Ren S, Collins CC, Nelson PS, Morrissey C, Wasan KM, Cox ME. Cancer Research. July 2019; DOI: 10.1158/0008-5472.CAN-18-2529
Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression. Hughes RM, Simons BW, Khan H, Miller R...Isaacs JT, Brennen WN, Park BH, Hurley PJ. Cancer Research. May 2019; DOI: 10.1158/0008-5472.CAN-18-2931
Targeting RET Kinase in Neuroendocrine Prostate Cancer. VanDeusen H, Ramropp JR, Morel KL...Morrissey C, Corey E, Nelson PS, Ellis L, Drake JM. bioRxiv. April 2019; DOI:
Prostate-Specific Loss of UXT Promotes Cancer Progression. Wang Y, Schafler ED, Thomas PA, Ha S, David G, Adney E, Garabedian MJ, Lee P, Logan SK. Oncotarget. January 2019; DOI: 10.18632/oncotarget.26573
DHX15 is Up-Regulated in Castration-Resistant Prostate Cancer and Required for Androgen Receptor Sensitivity to low DHT Concentrations. Xu Y, Song Q, Pascal LE, Zhong M, Zhou Y, Zhou J, Deng FM, Huang J, Wang Z. The Prostate. February 2019; DOI:
Role of a Novel-Race Related Tumor Suppressor microRNA Located in Frequently Deleted Chromosomal Locus 8p21 in Prostate Cancer Progression. Bhagirath D, Yang TL, Tabatabai ZL, Shahryari V, Majid S, Dahiya R, Tanaka Y, Saini S. Carcinogenesis Integrative Cancer Research. March 2019; DOI:
MicroRNA-644a Disrupts Oncogenic Transformation and Warburg Effect by Directly Downregulating Multiple Genes of Tumor-Promoting Pathways. Ebron JS, Shankar E, Singh J, Sikand K, Weyman CM, Gupta S, Linder DJ, Liu X, Campbell MJ, Shukla GC. Cancer Research. February 2019; DOI: 10.1158/0008-5472.CAN-18-2993
Targeting FOXA1-Mediated Repression of TGF-B Signaling Supresses Castration-Resistant Prostate Cancer Progression. Song B, Park SU, Zhao JC, Fong K, Li S, Lee Y, Yang YA, Sridhar S, Lu X, Abdulkadir SA, Vessella RL, Morrissy C, Kuzel TM, Catalona W, Yang X, Yu J. J Clin Invest. February 2019; DOI: 10.1172/JCI122367
Inhibition of De Novo Lipogenesis Targets Androgen Reeptor Signaling in Castration-Resistant Prostate Cancer. Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva...Adams J, Peluso S, Dehm S, Plymate SR, Loda M. Proc Natl Acad Sci USA. Jan 2019; DOI: 10.1073/pnas.1808834116
Therapeutic Considerations for Ron Receptor Expression in Prostate Cancer Brown NE, Sullivan C, Waltz SE. EMS Cancer Science Journal. July 2018; PMCID: PMC6377156
A Method to Quantify Centrosomes at Single-Cell Level in Human Normal and Cancer Tissue Wang M, Knudsen BS, Nagle RB, Rogers GC, Cress AE, Zheng Y. Molecular Biology of the Cell. January 2019;
Androgen Receptor Splice Variant-7 Expression Emerges with Castration Resistance in Prostate Cancer Sharp A, Coleman I, Yuan W, Sprenger C, Dolling D, Rodrigues DN, Russon JW, Figueiredo I, Dertan C, Seed G, Riisnaes R, Uo T, Neeb A, Welti J, Morrissey C, Carreira S, Luo J, Nelson PS, Balk SP, True LD, de Bono JS, Plymate SR. J Clin Invest. January 2019;
Adding the Team to T1 Translation Research: A Case Study of Multidisciplinary Team Science in the Evaluation of Biomarkers of Prostate Cancer Risk and Prognosis Marrone MT, Joshu CE, Peskoe SB, De Marzo AM, Heaphy CM, Lupold SE, Meeker AK, Platz EA. Clinical Chemistry. December 2018; doi: 10.1373/clinchem.2018.293365
Tumor-Infiltrating Mesenchymal Stem Cells: Driver of the Immunosuppressive Tumor Microenvirnoment in Prostate Cancer?Krueger TE, Thorek DLJ, Meeker AK, Isaacs JT, Brennen WN. The Prostate. November 2018; doi:
CD38 is Methylated in Prostate Cancer and Regulates Extracellular NAD+.Mottahedeh J, Haffner MC, Grogan TR, Crowell PD, Beltran H, Sboner A, Bareja R, Esopi D, Isaacs WB, Yegnasubramanian S, Rettig MB, Elashoff DA, Platz EA, De Marzo AM, Teitell MA, Goldstein AS. Cancer and Metabolism. September 2018; doi:
RNA-Binding Motif 3 Protein Expression and Nuclear Architecture Changes as a Combined Biomarker to Predict Aggressive and Recurrent Prostate Cancer.Carleton NM, Zhu G, Miller MC, Davis C, Veltri RW. Cancer Research Frontiers. July 2018; doi: 10.17980/2017.192
Abstract 1070: Discoidin Domain Receptor 1 (DDR1): A Potential Suppressor of Prostate Cancer Progression.Bonfil RD, Sohail A, Vranic S, Oliveria DS, Shi D, Chen W, Jang H, Saliganan AD, Wasinski BD, Kim HRC, Fridman RA. AACR. July 2018; doi: 0.1158/1538-7445.AM2018-1070
Effect of Preanalytic Variables on an Automated PTEN Immunohistochemistry Assay for Prostate Cancer.Guedes LA, Morais CL, Fedor H, Hicks J, Gurel B, Melamed J, Lee P, Gopalan A, Knudsen BS, True LD, Scher HI, Trock BJ, De Marzo AM, Lotan TL. Archines of Pathology and Laboratory Medicine. May 2018; doi:
Cell-type Specific Expression of Oncogenic and Tumor Suppressive microRNAs in the Human Prostate and Prostate Cancer.Kumar B, Rosenberg AZ, Choi SM, Fox-Talbot K, De Marzo AM, Nonn L, Brennen WN, Marchionni L, Halushka MK, Lupold SE. Sci Rep. May 2018; doi:
Notch3 Promotes Prostate Cancer-Induced Bone Osteoblastic Metastasis in an MMP-3-Dependent Manner.Ganguly SS, Hostetter G, Tang L, Frank S, Saboda K, Mehra R, Wang L, Li X, Keller ET, Miranti CK. Oncogene. June 2018; doi:
BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: hypothesis tested in race-specific models.Ganaie A, Beigh FH, Astone M, Ferrari MG, Maqbool R, Umbreen S, Parray AS, Siddique HR, Hussain T, Murugan P, Morrissey C, Koochekpour S, Deng Y, Konety B, Hoeppner L, Saleem M. Clinical Cancer Research, August 2018; doi:
Prostate cancer susceptibility gene HIST1H1A is a modulator of androgen receptor signaling and epithelial to mesenchymal transition.Williams KA, Lee M, Winter JM, Gildea DE, Calagua C, Curry NA, Lichtenberg J, Ye H, Crawford NPS. Oncotarget, June 2018; doi:
Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer.Zhu Y, Sharp A, Anderson CM, Silberstein JL, Taylor M, Lu C, Zhao P, De Marzo AM, Antonarakis ES, Wang M, Wu X, Luo Y, Su N, Rodrigues AN, Figueiredo I, Welti J, Park E, Ma XJ, Luo J. European Urology, May 2018; doi: 10.1016/j.eururo.2017.08.009
The identification of a novel antibody for CD133 using human antibody phage display.Glumac PM, Forster CL, Zhou H, Murugan P, Gupta S, LeBeau AM. The Prostate, May 2018; doi: 10.1002/pros.23656
ETS2 is a prostate basal cell marker and is highly expressed in prostate cancers aberrantly expressing p63.Torres A, Alshalalfa M, Davicioni E, Gupa A, Yegnasubramanian S, Wheelan SJ, Epstein JI, De Marzo AM, Lotan TL. The Prostate, May 2018; doi: 10.1002/pros.23646
Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtype of advanced prostate cancer.Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlshlegel J, Witte ON. PNAS, February 2018; doi: 10.1073/pnas.1802354115
Microsatellite instability in prostate cancer by PCR or next-generation sequencing.Hempelmann J.A, Lockwood C.M, Konnick E.Q, Schweizer M.T, Antonarakis E.S, Lotan T.L, Montgomery B, Nelson P.S, Klemfus N, Salipante S.J, Pritchard C.C. Journal for Immunotherapy of Cancer, April 2018; doi: 10.1186/s40425-018-0341-y
MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Rolde fo HOXB13 Binding Partners in Metastatic Disease. Bhanvadia R.D, VanOpstall C, Brechka H, Barashi N.S, Gillard N.S, Gillard M, McAuley E.M, Apiz J, Paner G.P, Chan W, Andrade J, De Marzo A, Han M, Szmulewitz R.Z, Vander Griend D..J. Clinical Cancer Research, May 2018; doi: 10.1158/1078-0432.CCR-17-3673
Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription. Jia L, Wu D, Wang Y, You W, Wang Z, Xiao L, Cai G, Xu Z, Zou C, Wang F, Yuen-Chun J, Ng C, Chen F. Oncogene, March 2018; doi: 10.1038/s41388-018-0198-z
PBOV1 as a potential biomarker for more advanced prostate cancer based on protein and digital histomorphometric analysis.Carleton NM, Zhu G, Gorbounov M, Miller MC, Pienta KJ, Resar LM, Veltri RW. The Prostate, March 2018; doi: 10.1002/pros.23499
MicroRNA-1246 is an exosomal biomarker for aggressive prostate cancer. Bhagirath D, Yang TL, Bucay N, Sekhon K, Majid S, Shahryari V, Dahiya R, Tanaka Y, Saini S. Cancer Research, December 2017; doi: 10.1158/0008-5472
MYC Targeted Long Non-Coding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels. Lu Y, Hu Z, Mangala KS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, DeMarzo A, Sood AK, Zhang L, Dang CV. Cancer Research, September 2017; doi: 10.1158
Arylsulfatase B is Reduced in Prostate Cancer Recurrences.Feferman L, Deaton R, Bhattacharyya S, Xie H, Gann PH, Melamed J, Tobacman JK. IOS Press Content Library, December 2017; doi: 10.3233
Identifying Dysregulated Epigenetic Enzyme Activity in Castrate-Resistant Prostate Cancer Development Lee JH, Yang B, Lindahl AJ, Damaschke N, Boersma MD, Huang W, Corey E, Jarrard DF, Denu JM. ACS, September 2017; doi: 10.1021
DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor Jing Y, Nguyen MM, Wang D, Pascal LE, Guo W, Xu Y, Ai J, Deng FM, Masoodi KZ, Yu X, Zhang J, Nelson JB, Xia S and Wang Z. Oncogene, February 2018; doi: 10.1038
Mesenchymal stem cell infiltration during neoplastic transformation of the human prostate W. Nathaniel Brennen, Baohui Zhang, Ibrahim Kulac, L. Nelleke Kisteman, Lizamma Antony, Hao Wang, Alan K. Meeker, Angelo M. De Marzo, Isla P. Garraway, Samuel R. Denmeade, John T. Issacs Oncotarget, February 2018; doi: 10.18632
Automated analysis of co-localized protein expression in histologic sections of prostate cancer Thomas A. Tennill, Mitchell E. Gross, Hermann D. Frieboes PLOS One, May 2017; doi: 10.371
Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations Franklin W. Huang, Juan Miguel Mosquera, Andrea Garofalo, Coyin Oh, Maria Baco, Ali Amin-Mansour, Bokang Rabasha, Samira Bahl, Stephanie A. Mullane, Brian D. Robinson, Saud Aldubayan, Francesca Khani, Beerinder Karir, Eejung Kim, Jeremy Chimene-Weiss, Matan Hofree, Alessandro Romanel, Joseph R. Osborne, Jong Wook Kim, Gissou Azabdaftari, Anna Woloszynska-Read, Karen Sfanos, Angelo M. De Marzo, Francesca Demichelis, Stacey Gabriel, Eliezer M. Van Allen, Jill Mesirov, Pablo Tamayo, Mark A. Rubin, Isaac J. Powell, and Levi A. Garraway Cancer Discovery, May 2017; doi: 10.1158/2159-8290.CD-16-0960
Differential Long-Term Stability of microRNAs and RNU6B snRNA in 12-20 Year Old Archived Formalin-Fixed Paraffin-Embedded Specimens Sarah B. Peskoe, John R. Barber, Qizhi Zheng, Alan K. Meeker, Angelo M. De Marzo, Elizabeth A. Platz and Shawn E. Lupold BMC Cancer, January 2017; doi: 10.1186/s12885-016-3008-4
Low Intratumoral Mast Cells are Associated with a Higher Risk of Prostate Cancer Recurrence Heidi A Hempel, Nathan S Cuka, Ibrahim Kulac, John R Barber, Toby C Cornish, Elizabeth A Platz, Angelo M De Marzo, Karen S Sfanos. The Prostate, March 2017; doi: 10.1002/pros.23280
α3β1 Integrin Suppresses Prostate Cancer Metastasis via Regulation of
the Hippo Pathway
Afshin Varzavand, Will Hacker, Deqin Ma, Katherine Gibson-Corley, Maria Hawayek, Omar J. Tayh, James A. Brown, Michael D. Henry and Christopher S. Stipp Cancer Research, September 2016; doi: 10.1158/0008-5472.CAN-16-1483
Prediction of Prostate Cancer Recurrence using Quantitative Phase Imaging: Validation on a General Population Shamira Sridharan, Virgilia Macias, Krishnarao Tangella, Jonathan Melamed, Emily Dube, Max Xiangtian King, Andre Kajdacsy-Balla and Gabriel Popescu Scientific Reports, September 2016; 6: 33818. doi: 10.1038/srep33818
Analytic Validation of RNA In Situ Hybridization (RISH) for AR and AR-V7 Expression in Human Prostate Cancer Liana B. Guedes, Carlos L. Morais, Fawaz Almutairi, Michael C. Haffner, Qizhi Zheng, John T. Issacs, Emmanuel S. Antonarakis, Changxue Lu, Harrison Tsai, Jun Lup, Angelo M. De Marzo, and Tamara L. Lotan Clinical Cancer Research, September 2016; DOI: 10.1158/1078-0432.CCR-16-0205
Identification of miR-30b-5p as Direct Regulators of Androgen Receptor Signaling in Prostate Cancer by Complementary Functional microRNA Library Screening Binod Kumar, Salar Khalenghzadegan, Brian Mears, Koji Hatano, Tarana A. Kudrolli, Wasim H. Chowdhury, David B. Yeater, Charles M. Ewing, Jun Luo, William B. Issacs, Luigi Marchionni and Shawn E. Lupold Oncotarget, September 2016; doi: 10.1158/0008-5472.CAN-16-1483
ACSL4 Promotes Prostate Cancer Growth, Invasion and Hormonal Resistance. Wu X, Deng F, Li Y, Daniels G, Du X, Ren Q, Wang J, Wang LH, Yang Y, Zhang D, Ye F, Melamed J, Monaco ME, Lee P Oncotarget, December 2015; doi: 10.18632/oncotarget.6438
A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells Shu-Han Yu, Qizhi Zheng, David Esopi, Anne Macgregor-Das, Jun Luo, Emmanuel S. Antonarakis, Charles G. Drake, Robert Vessella, Colm Morrissey, Angelo M. De Marzo, and Karen S. Sfanos Cancer Immunology Research, October 2015; 3(10):1175–84. doi: 10.1158/2326-6066.CIR-15-0013
Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment and are Differentially Associated with Metastatic Prostate Cancer Paula J. Hurley, Debasish Sundi, Brian Shinder, Brian W. Simons, Robert M. Hughes, Rebecca M. Miller, Benjamin Benzon, Sheila F. Faraj, George J. Netto, Ismael A. Vergara, Nicholas Erho, Elai Davicioni, R. Jeffrey Karnes, Guifang Yan, Charles Ewing, Sarah D. Isaacs, David M. Berman, Jennifer R. Rider, Kristina M. Jordahl, Lorelei A. Mucci, Jessie Huang, Steven S. An, Ben H. Park, William B. Isaacs, Luigi Marchionni, Ashley E. Ross, and Edward M. Schaeffer Clinical Cancer Research, Oct 7, 2015. doi: 10.1158/1078-0432.CCR-15-0256
A Novel Quantitative Multiplex Tissue Immunoblotting for Biomarkers Predicts a Prostate Cancer Aggressive Phenotype Guangjing Zhu, Zhi Liu, Jonathan I. Epstein, Christine Davis, Christhunesa S. Christudass, H. Ballentine Carter, Patricia Landis, Hui Zhang, Joon-Yong Chung, Stephen M. Hewitt, M. Craig Miller, and Robert W. Veltri Cancer Epidemiol Biomarkers Prev., Sept 24, 2015; 24(12):1864-72. doi: 10.1158/1055-9965.EPI-15-0496
Molecular Evidence That Invasive Adenocarcinoma Can Mimic Prostatic Intraepithelial Neoplasia (PIN) and Intraductal Carcinoma Through Retrograde Glandular Colonization Michael C. Haffner, Christopher Weier, MengMeng Xu, Ajay Vaghasia, Bora Gürel, Berrak Gümüşkaya, David M. Esopi, Helen Fedor, Hsueh-Li Tan, Ibrahim Kulac, Jessica Hicks, William B. Isaacs, Tamara L. Lotan, William G. Nelson, Srinivasan Yegnasubramanian, Angelo M. De Marzo The Journal of Pathology, Aug 31, 2015; 238(1):31–41. doi: 10.1002/path.4628
Overexpression of Periostin in Stroma Positively Associated with Aggressive Prostate Cancer Yuan Tian, Caitlin H. Choi, Qing Kay Li, Farah B. Rahmatpanah, Xin Chen, Sara Ruth Kim, Robert Veltri, David Chia, Zhen Zhang, Dan Mercola, Hui Zhang PLoS One, June 4, 2015; 10(6):e0130333. doi: 10.1371/journal.pone.0130333
A Gold Nanoparticle-Enabled Blood Test for Early Stage Cancer Detection and Risk Assessment Tianyu Zheng, Nickisha Pierre-Pierre, Xin Yan, Qun Huo, Alvin Almodovar, Felipe Valerio, Inoel Rivera-Ramirez, Elizabeth Griffith, David D Decker, Sixue Chen, and Ning Zhu ACS Appl. Mater. Inter., March 10th 2015; 7(12):6819-27. doi: 10.1021/acsami.5b00371
The Hippo Pathway Effector, YAP, Regulates Motility, Invasion and Castration- Resistant Growth of Prostate Cancer Cells Lin Zhang, Shuping Yang, Xingcheng Chen, Seth Stauffer, Fang Yu,Subodh M. Lele, Kai Fu, Kaustubh Datta, Nicholas Palermo, Yuanhong Chen, and Jixin Dong Mol. Cell. Biol., Feb 2015; 35(8):1350-62. doi:10.1128/MCB.00102-15
LEF1 Targeting EMT in Prostate Cancer Invasion is Mediated by miR-181a Jiaqian Liang, Yirong Li, Garrett Daniels, Karen Sfanos, Angelo De Marzo, Jianjun Wei, Xin Li, Wenqiang Chen, Jinhua Wang, Xuelin Zhong, Jonathan Melamed, Jun Zhao, and Peng Lee
Molecular Cancer Research, January 13, 2015; 5(3):1124-32. doi:10.1158/1541-7786.MCR-14-0503
Investigation of miR-21, miR-141, and miR-221 Expression Levels in Prostate Adenocarcinoma for Associated Risk of Recurrence After Radical Prostatectomy Qizhi Zheng, Sarah B. Peskoe, Judit Ribas, Fatema Rafiqi, Tarana Kudrolli, Alan K. Meeker, Angelo M. De Marzo, Elizabeth A. Platz, and Shawn E. Lupold Prostate, Dec 2014; 74(16):1655-62. doi: 10.1002/pros.22883
Tumour-infiltrating Gr-11 Myeloid Cells Antagonize Senescence in Cancer Diletta Di Mitri, Alberto Toso, Jing Jing Chen, Manuela Sarti, Sandra Pinton, Tanja Rezzonico Jost, Rocco D’Antuono, Erica Montani, Ramon Garcia-Escudero, Ilaria Guccini, Sabela Da Silva-Alvarez, Manuel Collado, Mario Eisenberger, Zhe Zhang, Carlo Catapano, Fabio Grassi and Andrea Alimonti Nature, 2014 Nov 6; 515(7525):134-137. doi: 10.1038/nature13638
AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer Emmanuel S. Antonarakis, Changxue Lu, Hao Wang, Brandon Luber, Mary Nakazawa, Jeffrey C. Roeser, Yan Chen, Tabrez A. Mohammad, Yidong Chen, Helen L. Fedor, Tamara L. Lotan, Qizhi Zheng, Angelo M. De Marzo, John T. Isaacs, William B. Isaacs, Rosa Nadal, Channing J. Paller, Samuel R. Denmeade, Michael A. Carducci, Mario A. Eisenberger, and Jun Luo N. Engl. J. Med., Sep 2014; 371:1028-1038. doi: 10.1056/NEJMoa1315815
AR-Regulated TWEAK-FN14 Pathway Promotes Prostate Cancer Bone Metastasis JuanJuan Yin, Yen-Nien Liu, Heather Tillman, Ben Barrett, Stephen Hewitt, Kris Ylaya, Lei Fang, Ross Lake, Eva Corey, Colm Morrissey, Robert Vessella, and Kathleen Kelly Cancer Res., Aug 2014; 74: 4306 - 4317. doi: 10.1158/0008-5472.CAN-13-3233
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